Hinchcliffe, originally from Oakville, Ont., slammed into the wall going into turn three at Indianapolis Motor Speedway. His car briefly slid on its right side before coming to rest upright.
Hinchcliffe sustained an injury to his upper thigh and is currently in surgery, according the Indianapolis Motor Speedway.
It was the third such crash during the practices. Helio Castroneves and Josef Newgarden went airborne in crashes last week that raised concerns about the safety of the new oval aero kits. And on Sunday, Ed Carpenter flipped his car on its side in practice leading up to Indy 500 qualifying before IndyCar officials announced changes to reduce power and speeds.
Hinchcliffe was scheduled to appear in Toronto on Tuesday. He is the featured driver in a Honda Indy Toronto event at Muzik on Exhibition Place grounds.
The 99th Indianapolis 500 is scheduled for next Sunday, May 24.