Lynne Carmody and Rick Moynan left for a hike at about 10 a.m. PT Monday.
They told the lodge they were staying at that they would be back by dinner time. When they did not return, the lodge staff conducted a search. They had no luck and called the RCMP Monday night.
Search and rescue volunteers began a search on Tuesday by foot, vehicle and air. Two helicopters and 14 people are involved in the search mission.
The camp where the two went missing is at approximately 2,000 metres elevation.
Carmody and Moynan are from North Bay, Ontario, according to their Facebook pages, and both are believed to be between 50 and 60 years of age.