Opinion polls showed Greeks evenly split on whether to accept creditors' proposals for more austerity in exchange for rescue loans, or defiantly reject the deal and send the message that they're simply fed up with years of harsh economic austerity.
With no campaigning allowed the day before the vote, the natural rhythm of daily life in the capital briefly replaced the sense of urgency that was palpable all week when Greeks struggled to decipher a convoluted referendum question whilst being bombarded with frenzied messages of impending doom or defiance.
Aris Spiliotopoulos, a 22-year-old who is launching his own tourism start-up, said he believes the vote is about whether Greece choses to stay among the club of nations that uses the euro as their currency and ultimately whether the country opts to stay in the European Union itself.
"I am voting 'yes' because I believe that my future and even my kids' future, in twenty or thirty years from now, is in the eurozone and the European Union," said Spiliotopoulos.
Gym teacher Alkiviadis Kotsis said he is voting "no" because the country and its people simply can't take more austerity.
"No matter how many loans you take, you cannot get by if you don't produce things. You can't do anything," he said.
Greece's high-stakes standoff with lenders saw the country default on debts this week, close banks to avoid their collapse, and lose access to billions of euros after an existing bailout deal expired.
Yet, Greek Prime Minister Alexis Tsipras insists a "no" vote will strengthen his hand to negotiate a third bailout with better terms.
No matter the referendum result, Tsipras faces a tough road ahead, fraught with uncertainty about whether he will be able to deliver an improved bailout agreement.
Yale University political science professor Stathis Kalyvas said the Greek government will face daunting challenges no matter which way the vote goes. In case of a "no" win, Kalyvas said the Greek government could be confronted with the refusal of other eurozone countries to negotiate a better deal because of their distrust of Tsipras.
A "yes" win won't mean a road to the negotiating table strewn with roses either, but would likely usher in a new government with a shot at negotiating an improved deal, Kalyvas said.
He said if the European Union wants to keep Greece in the eurozone, it will have to come up with "a very generous plan" since the cost of the crisis has shot up to unanticipated levels.
That was borne out by German Finance Minister Wolfgang Schaeuble, who told daily Bild Saturday that future negotiations between Greece and its creditors will be "very difficult," because the country's economic situation has worsened dramatically in recent weeks.
Schaeuble repeated the German government's position that for a community like Europe to work, all countries need to abide by the rules.
Meanwhile, Greece's Finance Minister Yianis Varoufakis launched a salvo at other eurogroup nations, accusing them of holding out on a bailout deal to allow bank coffers to run dry so they could spring a "vile ultimatum" on the government to accept what he called a humiliating deal.
Writing in the Saturday edition of daily Kathimerini, Varoufakis said other eurogroup members rejected Greece's "honourable" counter-proposals and insisted on extracting "humility."
Varoufakis said accepting the creditors' terms would be a "permanent condemnation" while rejecting it would offer the "only prospect for recovery."
With speculation swirling on the referendum's impact on Tsipras' government, Greece's Deputy Prime Minister Yiannis Dragasakis denied media reports that he would accept to lead a new "grand coalition" government.
"The country has a prime minister who will have an even stronger popular mandate and support. I will serve this mandate on my part," he said in a statement.
Online: Official referendum website http://www.referendum2015gov.gr/en/
Iuliia Subbotovskaia and Eftehia Katsareas in Athens contributed to this report.Suggest a correction