Natalie Achonwa added 13 in her first tournament with Canada since tearing the anterior cruciate ligament in her left knee last year.
Tamara Tatham chipped in with 10 points for the Canadians, whose depth and attention to defence made them the class of the tournament as they reeled off five wins in five nights.
The Canadians led by as many as 17 points in front of a delirious sell-out crowd of about 3,300 flag-waving fans at Ryerson University's Mattamy Athletic Centre.
The Americans would pull within five points twice in the fourth quarter, and trailed just 78-73 with 18 seconds to play.
A free throw by Achonwa and then two by Nurse with seven seconds left sealed Canada's victory.