The 23-year-old "Suicide Squad" star poses nude on the subscribers' cover of the men's magazine's September 2016 issue, donning nothing but a piercing gaze.
Photographed by Simon Emmett, the black and white image sees Delevingne sitting at the edge of a wooden table with her back to the camera. Her right arm covers up her breasts, and her butt cheeks are in full view.
The newsstand cover features a close-up shot of the model, with only half her face visible.
The rest of the accompanying shoot consists of more intimate photos of Delevingne, including close-ups of her feet, her face and yet another nude portrait.
The face of Saint Laurent is afraid to be nude, however. During her interview with the magazine, Cara shares a tale of a "spooky night spent naked and alone in the woods ... communing with the spirit world."
"Well, I wasn’t naked when I walked there. I walked there with my clothes on, and then when I got there I took them off," she explains, adding she wasn't really chilly since it was summer.
She also opened up about her real thoughts on the fashion industry, and why she would like to move on from modelling and be an actress or singer or therapist "her three exit plans, in that order," writes Esquire U.K.
"Modelling is not something I love. It always felt like a job. It was never a passion. It was more like a part I played," she said.
"There are some girls who are beautiful all the time, that’s just who they are. I’m not. I’m a weirdo, I’m a goofball," she continued. "I just don’t ever feel like I look that pretty. And so when I do all the posing, that just feels so stupid to me."