The publication says it analyzed more than 200 million comments and other travel references on the social network site to come up with the list.
The article says Penticton — nestled in the Okanagan Valley about a five hour drive east of Vancouver — is becoming a year-round vacation hot spot with its beautiful beaches, a burgeoning wine industry and many outdoor activities.
Eric Sorensen, chair of the Penticton Business Development Group, calls the ranking a "huge coup" for his city.
He says now the world knows about the area's natural assets and the local tourism business is looking forward to welcoming new visitors as a result of the article.
Portland, Oregon, and Charleston, South Carolina also made the list, along with cities in Spain, Columbia, Bolivia, Estonia, Croatia, Vietnam, and Laos.