That brings the total to four after two people died of the infection last week at the Cape Breton Regional Hospital in Sydney.
The authority says the latest victims also suffered from other illnesses.
Officials say eight patients are currently being treated for C. difficile.
However, the authority says there have been no new hospital acquired cases of the infection in the past 10 days.
Special cleaning for C. difficile continues in patient rooms, units and clinical areas of the hospital.