Ka'aihue's single off Mike Adams (0-2) drove in Jonny Gomes, who had three hits. Josh Reddick's 10th homer off Alexi Ogando made it 4-all in the seventh.
Ryan Cook (1-0) escaped a ninth-inning jam and has pitched 19 2-3 scoreless innings this season, most among AL relievers. Brian Fuentes recorded his third save.
Oakland fell behind 4-3 in the sixth when Craig Gentry scored from third on a squeeze bunt that Brandon McCarthy thought he caught. A's manager Bob Melvin was ejected for arguing the call.
BLUE JAYS 4, YANKEES 1
TORONTO (AP) — Jose Bautista and J.P. Arencibia each hit a two-run homer, Drew Hutchison won consecutive starts for the first time and Toronto swept a two-game series from the Yankees.
New York lost its third straight and fell to 0-9 this season when failing to hit at least one home run. The Yankees, who have scored 12 total runs in nine losses this month, dropped into fourth place in the AL East.
Making his sixth major league start, Hutchison (3-1) allowed one run and five hits in six innings. Casey Janssen finished for his second save.
Bautista hit his second homer in two nights and 10th this season. He connected off Phil Hughes (3-5), who went 5 1-3 innings and lost for the first time in three starts.
RED SOX 5, RAYS 3
ST. PETERSBURG, Fla. (AP) — Cody Ross homered and drove in four runs, Felix Doubront won his third consecutive start and Boston snapped Tampa Bay's four-game winning streak.
Ross extended the lead to 5-2 on a two-run single off reliever Wade Davis with two outs in the eighth.
Doubront (4-1) allowed two runs and six hits over 5 2-3 innings. The left-hander was hit on the ear by a ball during batting practice Tuesday and cleared one day later to make his scheduled start.
Alfredo Aceves, the fifth Boston reliever, got four outs for his eighth save.
Matt Moore (1-4) gave up three runs and five hits in six innings.
TWINS 4, TIGERS 3
DETROIT (AP) — Justin Morneau of New Westminster, B.C., hit a two-run homer in his second game back from a wrist injury, and the Twins swept the two-game series at Comerica Park.
P.J. Walters (1-1) allowed four hits — including three solo homers — in 6 1-3 innings for the Twins Park. Minnesota (12-26) has won two in a row for only the second time this season.
Morneau's homer off Doug Fister (0-2) opened the scoring in the third, and Trevor Plouffe followed with a long ball. Minnesota led 4-0 before the Tigers came back with homers by Brennan Boesch, Andy Dirks and Prince Fielder.
ORIOLES 5, ROYALS 3
KANSAS CITY, Mo. (AP) — Adam Jones hit a two-run homer, J.J. Hardy also drove in a pair of runs and the Orioles beat the Royals for their seventh straight road win.
The Orioles also improved to 12-1 when Jones goes deep, including a victory over the Royals the previous night, when his homer in the 15th inning decided the game.
Brian Matusz (3-4) won for the third time in four starts after enduring a career-worst 12-decision losing streak. He allowed three runs on seven hits and a walk in six innings.
Luke Hochevar (3-4) pitched well for six innings. His only real miscue was the two-run homer by Jones in the fourth.
INDIANS 6, MARINERS 5, 11 INNINGS
CLEVELAND (AP) — Carlos Santana hit a game-ending single with one out and the bases loaded in the 11th inning, capping a two-run rally and lifting the Indians to a victory over Seattle.
Michael Saunders' run-scoring double in the top of the inning gave Seattle a 5-4 lead, but closer Brandon League (0-3) couldn't hold the lead.
Jose Lopez, who tied the game in the eighth with a three-run homer, drew a leadoff walk and went to second on a wild pitch. After Shin-Soo Choo struck out, Jason Kipnis walked. Asdrubal Cabrera's single to right tied it.
Joe Smith (4-1) got the win despite allowing the go-ahead run in the top of the 11th.
WHITE SOX 6, ANGELS 1
ANAHEIM, Calif. (AP) — Chris Sale pitched effectively into the sixth inning, giving Chicago's rotation a much-needed solid outing, and the White Sox capitalized on some shoddy defence by the Los Angeles Angels for a victory.
After a three-game stretch in which starters John Danks, Jake Peavy and Gavin Floyd gave up a combined 18 earned runs over 14 1-3 innings, Sale (4-2) restored order in his sixth major league start. The 23-year-old left-hander struck out seven and was working on a three-hit shutout in the sixth when he gave up a one-out homer to Albert Pujols and a double to Mark Trumbo and was replaced by Nate Jones. Trumbo had a career-high four hits.
C.J. Wilson (4-4) threw 88 pitches in 3 2-3 innings and tied a career high with six walks. He was charged with four runs — one earned — and four hits.