Bautista immediately grabbed his left wrist and dropped into a crouch outside the batter's box after hitting a long foul ball against David Robertson. Several members of Toronto's staff attended to Bautista, who was tied for second in the majors with 27 homers.
After a few minutes, he walked off the field holding his wrist and Ben Francisco took over at bat with a 2-1 count. Francisco walked.
After the game, the Blue Jays said Bautista did not break a bone. But he has a tendon injury and will have an MRI on Tuesday to determine how severe it is.
Bautista was 0 for 2 with a walk and a run scored. The Blue Jays lost 6-3.