Carlos Delfino added 21 points and Luis Scola had 20 as Argentina's NBA stars pounded winless Tunisia. Scola plays for the Phoenix Suns and Delfino is with the Milwaukee Bucks.
Tunisia led by 14 after the first quarter. But Ginobili, the San Antonio Spurs star, scored 12 points in a 15-0 run at the start of the second quarter that gave Argentina a 29-28 lead.
But Tunisia battled back and the game was tied 40-40 at halftime.
Ginobili hit a 3-pointer to start the second half and Argentina took the lead and never trailed again.
Salah Mejri finished with 19 points for Tunisia and Mourad El Mabrouk had 16.