John Geddert said Tuesday she has been dealing with pain in the leg since the U.S. women's pre-Olympic training camp, which began the second week of July.
Wieber came into the Olympics as a favourite to win multiple medals, but she leaves London without any individual medals after finishing seventh on floor exercise.
She failed to make the all-around final after finishing fourth in qualifying. Countries are limited to two gymnasts in individual finals, and teammates Aly Raisman and Gabby Douglas finished ahead of Wieber.
Wieber does have a gold medal, however, from the team victory, the first Olympic title by a U.S. women's squad since 1996.