RCMP Cpl. Holly Marks said an industrial accident Tuesday set fire to a building and several truck trailers at a trucking operation.
"The initial explosion of unknown chemicals has triggered a chain of smaller explosions currently being addressed," she said.
"There is currently no power in the area due to several hydro transformers having blown."
The fire belched out a thick, black plume of smoke that has forced the evacuation of nearby businesses and residents for several blocks around.
Rail and vehicle traffic has been closed off in the area, and southbound traffic on the nearby Golden Ears Bridge was shut down for about two hours.
BC Ambulance Service spokeswoman Kelsie Carwithen said the injured person was airlifted to Vancouver General Hospital.
"As far as I know, no other patients have been transported as of yet but the incident is still unfolding so you can imagine that may change," she said, adding the incident began at about 2:30 p.m.
Officials from Transport Canada and WorkSafeBC are on the scene.