After winning the last six races in North America, including the first three this year with rookie brakeman Chelsea Valois of Zenon Park, Sask., the 27-year-old Humphries continued her torrid pace by claiming her fourth straight gold medal of the pre-Olympic season.
"I am very happy to keep the streak going in Germany," Humphries said. "I think that was very important for me. I haven't always had a lot of success in Winterberg because it is so weather dependent here. The weather was perfect and we had good pushes and good runs today."
It was Humphries' eighth career World Cup victory to go along with her Olympic and world championship titles, bringing her career World Cup medal total to 15.
"I had a lot of confidence going into the race, but the weather can change everything," she added. "Chelsea and I had two of our best starts to go along with two good runs down the track so I'm happy with how things turned out."
Elana Meyers and Katie Eberling of the U.S. finished second, while Germany's Anja Schneiderheinze and Stephanie Schneider were third.
Meanwhile in the men's two-man race, Lyndon Rush of Humboldt, Sask., continued his own medal streak. The 32-year-old, who won the silver two weeks ago in Whistler, B.C., with Lascelles Brown, teamed up with Jesse Lumsden of Burlington, Ont., to win the bronze after posting a combined time of 1:51.41.
It was the fourth World Cup medal for the Canadian duo since teaming up last year.
"We normally find the Winterberg track really difficult, but our runs worked out really well today," Rush said. "I'd like to say a big thank you to my whole team."
It was the fourth two-man, and eighth overall World Cup medal of Rush's career to go along with his Olympic bronze and world championship silver that he won with Lumsden last year in Lake Placid, N.Y.
Switzerland's Beat Hefti and Tomas Lamparter won the gold Saturday with a time of 1:51.01, while Russia's Alexander Zubkov and Dmitry Trunenkov took silver in 1:51.32.
Hefti missed the first three races in North America because his usual brakemen were injured.
The World Cup continues on Sunday with the men's four-man races.