The group banged drums, sang and carried signs as they walked from the St. Mary's First Nation and marched through Fredericton.
St. Mary's Chief Candice Paul says they presented Nicholas with three letters they want forwarded to the Queen, the Governor General and Prime Minister Stephen Harper.
She says the letters express their concerns with the federal government's recently passed omnibus budget legislation and its effect on the environment.
Nicholas — a member of the Tobique First Nation — spoke to the crowd in Maliseet and English, telling them to take care of themselves and agreeing to forward their letters.
He said the beauty of Canada's democracy is the ability to have large, peaceful demonstrations and be heard.
A separate protest was held in Miramichi in northern New Brunswick, where 175 people marched across the Centennial Bridge.
Police say traffic was rerouted and the group was peaceful.
Note to readers: This is a corrected story. A previous version had an incorrect spelling for the St. Mary's Chief.