TED, which stands for the Technology, Entertainment, Design conference, is held each year in Long Beach, Calif., but Vancouver will play host in 2014.
A parallel forum called the TEDActive conference will also shift from Palm Springs to Whistler.
Past TED conferences have included a variety of speakers from former U.S. president Bill Clinton to Apple founder Steve Jobs and Microsoft founder Bill Gates.
The speeches are posted online where they've gained a wide following around the world.
Mayor Gregor Robertson says having the TED conference come to Vancouver is a big vote of confidence in the creative, social and community leaders who make it a leading-edge city.