James shot 9 for 11, giving him 37 makes on his last 47 attempts, and sat out the fourth quarter. It was his fourth straight 30-point game, tying him with Wade as the only Heat player with such streaks in the franchise's 25-year history.
Mario Chalmers finished with 18 points and Shane Battier scored 12 for Miami, which improved to 21-3 at home.
The Clippers got Chauncey Billups, Chris Paul and Blake Griffin back from injuries, but that trio of starters combined for only 23 points. DeAndre Jordan led Los Angeles with 17 points.
Miami was without Chris Bosh and Ray Allen, both sidelined with the flu.
LAKERS 100, BOBCATS 93
CHARLOTTE, N.C. (AP) — Kobe Bryant shrugged off a scoreless first half to finish with 20 points, eight assists and seven rebounds and Los Angeles overcome a 20-point second-half deficit to beat Charlotte.
The Lakers avoided a costly defeat to the NBA's worst team and pulled within three games of .500.
Bryant attempted only two shots in the first half and didn't come out for warmups to start the second. But he provided the jolt the Lakers needed in the third quarter and scored 14 points in the final period, including a driving layup with 40 seconds left to push the lead to five.
Steve Nash and Earl Clark each scored 17 points and Dwight Howard added 12 points, all in the first half, and 11 rebounds for the Lakers (24-27).
Byron Mullens and Gerald Henderson each had 20 points for the Bobcats, who have lost six straight.
PISTONS 119, SPURS 109
AUBURN HILLS, Mich. (AP) — Greg Monroe had 26 points and 16 rebounds as Detroit snapped San Antonio's 11-game winning streak with a victory over the short-handed Spurs.
San Antonio played without Tim Duncan and Manu Ginobili, and the Pistons led by as many as 21 points in the second quarter. It was 65-52 at halftime, and although the Spurs cut the deficit to seven in the fourth, they fell short against a Detroit team that equaled its highest point total of the season.
Tony Parker scored 31 points for San Antonio and Kawhi Leonard added 16. Brandon Knight had 24 for the Pistons, and Charlie Villanueva scored 21.
Detroit was without rookie big man Andre Drummond, who is expected to miss four to six weeks because of a stress fracture in his back.
KNICKS 100, TIMBERWOLVES 94
MINNEAPOLIS (AP) — Carmelo Anthony had 36 points and nine rebounds, scoring 12 points down the stretch to rally New York over Minnesota.
Anthony topped 30 points for the 17th time this season for the Knicks, who trailed by 11 with seven minutes to play. But Anthony did all his fourth-quarter damage in those final minutes, hitting a 19-footer with 1:10 to play that put New York up for good.
Derrick Williams scored 19 points and Ricky Rubio had 18 points and 11 assists for the Timberwolves, who lost for the 14th time in 16 games.
Nikola Pekovic added 16 points and 11 rebounds, but Minnesota had no answer for Anthony down the stretch.
THUNDER 127, PHOENIX 96
OKLAHOMA CITY (AP) — Kevin Durant scored 21 points, Thabo Sefolosha had a season-high 18 and Oklahoma City rode a gigantic third-quarter run to a victory over Phoenix.
All five Thunder starters had at least one basket during a 21-0 run that put Oklahoma City in position to complete a perfect homestand with a third straight blowout. Russell Westbrook had a right-handed slam during the run before finishing it off with a banked-in runner to stretch the lead to 81-55 with 3:25 to go in the third quarter.
Phoenix even came out of a timeout with six players on the floor at one point during the stretch, but all that did was result in another point after Durant made the resulting technical foul.
Michael Beasley led the Suns with 25 points.
BULLS 93, JAZZ 89
SALT LAKE CITY (AP) — Carlos Boozer scored 19 points, including 11 straight in the fourth quarter, and Chicago closed out a six-game road trip with a victory over Utah.
Nate Robinson added 18 points for the Bulls, who rebounded nicely from a 32-point loss in Denver 24 hours earlier.
Al Jefferson had a season-high 32 points for Utah, scoring the first eight in the fourth period to give the Jazz a 77-73 lead.
Boozer, plagued by foul trouble early, got rolling with about 5 minutes remaining against his former team. His layup tied it at 83 with 2:29 left and he scored the next five from the free throw line, including a pair with 27 seconds left for an 88-85 Bulls lead.
Randy Foye's layup pulled Utah to 88-87 with 22 seconds left, but Chicago sealed it at the foul line.
GRIZZLIES 99, WARRIORS 93
MEMPHIS, Tenn. (AP) — Marc Gasol scored six of his 20 points down the stretch to help Memphis beat Golden State.
Gasol, who also grabbed 11 rebounds, was 9 of 14 from the field to help the Grizzlies end a two-game slide. Tony Allen had 17 points on 7-of-8 shooting, Zach Randolph added 16 points and 12 rebounds, and Jerryd Bayless finished with 14 points.
Stephen Curry had 32 points and eight assists for the Warriors, who lost their third straight. David Lee was the only other Golden State player in double figures with 26 points, connecting on 10 of 16 shots.
Memphis took over with nine unanswered points after consecutive 3-pointers from Curry gave the Warriors their last lead of the game with about 8 minutes left.
ROCKETS 118, TRAIL BLAZERS 103
HOUSTON (AP) — James Harden had 35 points and 11 assists, and Chandler Parsons scored 20 to help Houston beat Portland.
Harden went 13 for 16 from the field and 4 of 5 from 3-point range, putting on an individual show in the last game at the Toyota Center before the NBA's All-Star weekend comes to town. Harden was chosen as a reserve for the West squad, making his first All-Star team.
LaMarcus Aldridge, another All-Star reserve for the West, scored 31 points for Portland. The Blazers had won the previous two meetings this season in overtime, rallying from double-digit deficits in both.
RAPTORS 100, PACERS 98, OT
INDIANAPOLIS (AP) — Rudy Gay scored 17 of his 23 points in the fourth quarter and overtime, rallying Toronto past weary Indiana.
The game went into overtime after Amir Johnson's buzzer-beating tip-in stood following a replay review. The Raptors won it when Gay hit a 17-foot jumper with 1.7 seconds left and Paul George's 15-footer rimmed out as the horn sounded.
David West scored 30 points and George had 26 as the Pacers' 15-game home winning streak came to an end.
DeMar DeRozan scored 22 to make Toronto (18-32) the first team to win twice at Indiana (31-20) this season.
WIZARDS 89, NETS 74
WASHINGTON (AP) — The Washington Wizards held Brooklyn without a field goal for nearly 9 minutes during the first half, withstood a second-half slump and held on for their latest win over a team near the top of the standings.
Nene had 20 points and 11 rebounds, John Wall added 15 points and nine assists, and Martell Webster scored 16 points for the Wizards, who have one of the worst records in the NBA but have nevertheless taken eight of their last nine at home — a stretch that includes wins over Oklahoma City, Atlanta, Chicago, New York and the Los Angeles Clippers.
Deron Williams scored 20 points for the Nets, who lost to a sub-.500 team for only the second time this season. They fell apart quickly in this one: After a first quarter that included 10 lead changes, Brooklyn went 0 for 12 from the field to start the second and trailed 51-31 at halftime.
HORNETS 111, HAWKS 100
ATLANTA (AP) — Greivis Vasquez had his first career triple-double and Eric Gordon scored 27 points, leading New Orleans over Atlanta to give the last-place Hornets a rare winning streak.
Vasquez scored 21 points, dished out 12 assists and grabbed 11 rebounds for New Orleans, which rallied from a 14-point deficit in the first half and withstood a late charge by the stumbling Hawks.
Al Horford drove for a slam that cut the Hornets' lead to 98-94 with 3 1/2 minutes remaining. But Ryan Anderson sank a 3-pointer that caught the front of the rim, bounced high off the backboard and fell through. Anderson pumped his right fist; the Hawks never got closer than five the rest of the way.
Josh Smith led Atlanta with 23 points and Jeff Teague added 21.
Coming off a home victory over Phoenix, the young Hornets have just their fourth winning streak of the season.
CAVALIERS 119, MAGIC 108
CLEVELAND (AP) — Kyrie Irving scored 24 points and Cleveland sent Orlando to its 12th straight loss.
Marreese Speights had 18 points and Tristan Thompson added 16 for Cleveland, which scored 13 straight points in a stretch that began late in the third period to take control of the game.
The Cavaliers scored the last eight points of the third to go ahead 85-80. A basket by Shaun Livingston and a 3-pointer by Wayne Ellington put Cleveland ahead 90-80 early in the fourth. The Cavaliers scored 34 points in the final period.
Nikola Vucevic scored a career-high 25 points for Orlando, which has lost 23 of 25. The Magic haven't won since Jan. 16.