Boston's players were already en route to Cleveland when they learned of the explosions near the Boston Marathon's finish line that killed three and injured more than 170. The Red Sox were hoping to bring some relief to those affected by the tragedy, and they may have while winning their fourth straight.
The series opener was also Indians manager Terry Francona's first game against the Red Sox, the team he led to two World Series titles during eight seasons in Boston.
Helped by five walks, the Red Sox scored seven runs in the second off Ubaldo Jimenez (0-2) and gave Felix Doubront (1-0) all the support he needed.
Monday's tragic events in Boston brought a sombre tone to Francona's reunion as well as to the Red Sox. Before the game, in a clubhouse devoid of its usual pregame sound and bustle, several players spoke of how a memorable Patriots Day win over Tampa Bay turned horrific.
ORIOLES 5, RAYS 4
BALTIMORE (AP) — Matt Wieters homered, Nate McLouth scored twice, and the Baltimore Orioles beat the struggling Tampa Bay Rays despite allowing three home runs.
The Orioles let a four-run cushion dwindle to 5-4 in the eighth, but held on for their fifth straight home win over the Rays, dating to last year.
Desmond Jennings homered on the game's first pitch for Tampa Bay, and Kelly Johnson and Evan Longoria connected off Pedro Strop in the eighth. But the Rays could muster only six hits against Jake Arrieta (1-2) and five relievers.
Roberto Hernandez (0-3) took the loss for last-place Tampa Bay, which has lost four straight and seven of eight. With a 4-9 record, Tampa Bay has matched the worst start in franchise history (2001 and 2005).
WHITE SOX 4, BLUE JAYS 3
TORONTO (AP) — Dayan Viciedo doubled home the go-ahead run in the ninth inning and the Chicago White Sox rallied to beat the Toronto Blue Jays.
Paul Konerko hit a game-tying homer and scored three runs as the White Sox won for just the second time in eight games. Matt Lindstrom (1-0) got one out for the win and Addison Reed finished for his fifth save in as many opportunities.
Colby Rasmus and J.P. Arencibia hit solo home runs for the Blue Jays, who couldn't hold on after taking a 2-1 lead in the sixth. Steve Delabar (1-1) allowed two runs and one hit in 1 1-3 innings.
TWINS 8, ANGELS 6
MINNEAPOLIS (AP) — Joe Mauer had another four hits and three RBIs to lead the Minnesota Twins past the Los Angeles Angels.
Mauer sprayed four singles into the Target Field outfield, making him 8 for 10 in the series through two games and raising his average to .386. Brian Dozier added two hits and two RBIs in his first career game batting leadoff for the Twins.
Mike Pelfrey (2-1) gave up four runs and seven hits in five innings for the Twins. Jason Vargas (0-2) gave up five runs and nine hits with two walks in just 3 1/3 innings for the Angels.
ATHLETICS 4, ASTROS 3
OAKLAND, Calif. (AP) — Josh Donaldson's eighth-inning triple drove in Josh Reddick for the winning run and Oakland Athletics overcame starter A.J. Griffin's early struggles for a victory over the Houston Astros.
Reddick drew a two-out walk off reliever Rhiner Cruz (0-1) and took off for second just before Donaldson's hit down the right-field line landed just fair. Houston outfielder Rick Ankiel made a diving attempt, but came up short as Reddick raced around the bases.
Eric Sogard added a career-high three hits for the A's, who have won all five games against the Astros this season.
Carlos Pena homered for Houston, which has lost four straight. Grant Balfour pitched the ninth for his second save in as many chances after Sean Doolittle (1-0) gave up Pena's tying home run.
TIGERS 6, MARINERS 2
SEATTLE (AP) — Miguel Cabrera hit a two-run homer and drove in Detroit's first four runs, and the Tigers beat the Seattle Mariners.
Cabrera's homer came with two outs in the fifth inning off Seattle starter Aaron Harang (0-1) and was his second of the season. Cabrera drove a pitch off the edge of the plate out to right-centre field to give the Tigers a 3-2 lead. Cabrera also had RBIs in the first and seventh innings. Austin Jackson scored twice, giving him 19 runs scored in just 13 games.
Doug Fister (3-0) pitched seven strong innings for his first victory against his former team.
YANKEES 4, DIAMONDBACKS 2
NEW YORK (AP) — Robinson Cano paid tribute to Jackie Robinson in fitting fashion by hitting a three-run homer, and the New York Yankees beat the Arizona Diamondbacks on a night devoted to honouring victims of the Boston Marathon bombings.
Cano, whose big league father Jose named him for Robinson, connected on the day when all players, managers, coaches and umpires at Yankee Stadium wore No. 42 to salute the late Brooklyn Dodgers Hall of Famer. Major League Baseball held Jackie Robinson Day on Monday, the anniversary of the date he broke the colour barrier in 1947. The Yankees and Diamondbacks were off Monday.
Mariano Rivera, the last big leaguer still wearing No. 42 on a daily basis, closed for his third save.
The Yankees also remembered Boston, home of their longtime rivals, by playing the Fenway Park favourite "Sweet Caroline" after the third inning. Yankees fans sang along with the Neil Diamond hit as it came over the public-address system, and some people in the crowd wore Red Sox hats and jerseys.
Ivan Nova (1-1) laboured through five innings for the win. Brandon McCarthy (0-2) took the loss.