SAVAR, Bangladesh - Crews bored deeper Friday into the wreckage of a garment-factory building that collapsed two days earlier, hoping for miracle rescues that would prevent the staggering death toll from rising much higher, as angry relatives of the missing clashed with police.
Some of those trapped under fallen concrete in the Rana Plaza building were still alive, rescue workers said, but they were so badly hurt and weakened that they will need to be extricated within a few hours if they are to survive.
Rescue workers had to cut off Mussamat Anna's mangled right hand to pull the 18-year-old garment worker free from the debris Thursday night.
"First a machine fell over my hand and I was crushed under the debris. ... Then the roof collapsed over me," she told an Associated Press cameraman from a hospital bed Friday.
Brig. Gen. Mohammed Siddiqul Alam Shikder, who is overseeing rescue operations, said the death toll at the building had reached 290, and that 2,200 people have been rescued. The garment manufacturers' group said the factories in the building employed 3,122 workers, but it was not clear how many were inside it when it collapsed Wednesday in Savar, a suburb of Bangladesh's capital, Dhaka.
Hundreds of rescuers, some crawling through the maze of rubble, spent a third day working amid the cries of the trapped and the wails of workers' relatives gathered outside the building, which housed numerous garment factories and a handful of other companies.
Police cordoned off the building site, pushing back thousands of bystanders and relatives, after rescue workers said the crowds were hampering their work.
Clashes erupted between relatives of those still trapped and police officers, who used batons to disperse the mobs. Police said 50 people were injured in the clashes.
"We want to go inside the building and find our people now. They will die if we don't find them soon," said Shahinur Rahman, whose mother is missing.
An army rescue worker, Maj. Abdul Latif, said he found one survivor still trapped under concrete slabs, surrounded by several bodies. At another place in the building, four survivors were found pinned under the debris, a fire official said.
The rescue workers said they were proceeding very cautiously inside the crumbling building, using their hands, hammers and shovels, to avoid more injuries to trapped survivors and avoid further collapses.
Police say cracks in the building had led them to order an evacuation of the building the day before it fell, but the factories ignored the order.
A military official, Maj.-Gen. Chowdhury Hasan Suhrawardy, told reporters that search and rescue operations would continue until at least Saturday.
"We know a human being can survive for up to 72 hours in this situation. So our efforts will continue non-stop," he said.
Some people have been pulled out of the wreckage alive, though severely weakened, more than a day after the collapse.
Forty people had been trapped on the fourth floor of the building until rescuers reached them Thursday evening. Twelve were soon freed, and crews worked to get the others out safely, said Brig.-Gen. Mohammed Siddiqul Alam Shikder, who is overseeing rescue operations. Crowds at the scene burst into applause as survivors were brought out.
The odour of decaying bodies at the site is a constant reminder that many garment workers were not so lucky.
Thousands of workers from the hundreds of garment factories across the Savar industrial zone and other nearby industrial areas have taken to the streets to protest the collapse and poor safety standards.
Local news reports said protesters had smashed dozens of vehicles at one strike Friday. Most of the other protests were largely peaceful.
The disaster is the worst ever for Bangladesh's booming and powerful garment industry, surpassing a fire five months ago that killed 112 people and brought widespread pledges to improve the country's worker-safety standards.
Instead, very little has changed in Bangladesh, where wages, among the lowest in the world, have made it a magnet for numerous global brands.
Bangladesh's garment industry was the third-largest in the world in 2011, after China and Italy. It has grown rapidly in the past decade, a boom fuelled by Bangladesh's exceptionally low labour costs. The country's minimum wage is now the equivalent of about $38 a month.
Officials said soon after the collapse that numerous construction regulations had been violated.
Abdul Halim, an official with Savar's engineering department, said the owner of Rana Plaza was originally allowed to construct a five-storey building but added another three storeys illegally.
Home Minister Muhiuddin Khan Alamgir has said the building violated construction codes and that "the culprits would be punished." Local police chief Mohammed Asaduzzaman said police and the government's Capital Development Authority have filed separate cases of negligence against the building's owner.
Habibur Rahman, police superintendent of the Dhaka district, identified the owner of the collapsed building as Mohammed Sohel Rana, a local leader of ruling Awami League's youth front. Rahman said police were also looking for the owners of the garment factories.
Canadian clothing line Joe Fresh was among the western customers of the garment factories operating in the building.
Britain's Primark acknowledged it was using a factory in Rana Plaza, but many other retailers distanced themselves from the disaster, saying they were not involved with the factories at the time of the collapse or had not recently ordered garments from them.
Wal-Mart said none of its clothing had been authorized to be made in the facility, but it is investigating whether there was any unauthorized production.
U.S. State Department spokesman Patrick Ventrell said the collapse underscored the "urgent need" for the Bangladesh government, as well as the factory owners, buyers and labour groups, to improve working conditions in the country.
Human Rights Watch says Bangladesh's Ministry of Labor has only 18 inspectors to monitor thousands of garment factories in the sprawling Dhaka district, where much of the nation's garment industry is located.
John Sifton, the group's Asia advocacy director, also noted none of the factories in the Rana Plaza were unionized, and had they had been, workers would have been in a better position to refuse to enter the building on Wednesday.