Curbs will be painted red to mark the areas where parking is not allowed.
The intent of the pilot project is to help improve traffic flow, to make it clear where drivers can park and improve pedestrian safety.
"It's about clarity because parking signage can be confusing or unclear," Ford told reporters on Tuesday morning.
The mayor said the pilot project will be introduced at nine sites in Toronto and run for six to eight months. After that, city staff will evaluate the results.