Some provinces have expressed concern about how the deal will affect pharmaceutical, dairy, wine and spirits industries.
But Selinger says the deal will have a positive impact on Manitoba and could generate up to $200 million for the economy.
He says Manitoba was concerned the deal wouldn't have strong enough drug patent protection but he says the language has been strengthened.
Selinger says officials will be reviewing the deal in the coming days to ensure it's in the best interests of Manitoba.
Prime Minister Stephen Harper announced the agreement-in-principle with the European Commission president in Brussels today.