The parade is set to begin Saturday morning. The players will climb aboard 24 amphibious vehicles at Fenway Park and travel through the city before going into the Charles River.
Security will be tight during the event, with extra police on hand throughout the day and random searches of backpacks along the parade route.
The Massachusetts Bay Transportation Authority plans to run extra trains and subways at a rush-hour level.
The Red Sox beat the St. Louis Cardinals 6-1 at Fenway on Wednesday to take the best-of-seven series in six games.