Bryzgalov made the save with 3:41 left in the second period on Sunday but was then replaced by Devan Dubnyk. The Oilers announced on Twitter that Bryzgalov sustained an upper-body injury and wouldn't return to the game.
Bryzgalov stopped a forehand shot by Garbutt, but as the puck slid away to the left, Bryzgalov fell face forward onto the ice next to the net and appeared to hold his head.
After a visit from a trainer, he was helped off the ice.
Playing in just his fourth game this season, Bryzgalov made 28 saves and trailed 1-0 when he left the game.