The agency says Hamilton was the top contributor to the national increase, with prices rising 0.6 per cent in October.
Builders there cited market conditions and higher list prices for new phases of development as the reasons for the price increase.
The largest monthly price increase in October occurred in Windsor, where prices were up 0.7 per cent.
Builders in Windsor said rising material costs, higher land development costs and market conditions contributed to the gain.
Prices declined in Charlottetown, Vancouver and Victoria and were unchanged in seven of the 21 metropolitan areas surveyed.