The Office of the Chief Provincial Public Health said as of Thursday there were 45 cases of lab-confirmed influenza.
No confirmed influenza-related deaths this season have been reported.
The flu is an infection caused by a virus and spreads easily from one person to another through coughing, sneezing or sharing food or drinks.
People can also get the flu by touching objects contaminated with flu virus and then touching your mouth, eyes or nose.
This year's seasonal flu vaccine protects against H1N1 influenza A, as well as two other strains of the flu.
Manitobans who have not yet received their flu shot this year can contact their health-care provider or community public health clinic to make arrangements.