But the former NSA contractor won't appear in person at the conference in Austin on Monday.
He'll participate remotely via video as Snowden remains in Moscow where he's living in temporary asylum.
Snowden faces felony charges in the U.S. after revealing the agency's mass surveillance program by leaking thousands of classified documents to media outlets.
Christopher Soghoian, principal technologist at the American Civil Liberties Union, will be speaking to Snowden along with Snowden's legal adviser, the ACLU's Ben Wizner. The session begins at 11 a.m. Central Time.
The ACLU will offer a live blog of Snowden's talk on its website and the Texas Tribune's website will host a live video stream.
Fugitive WikiLeaks founder Julian Assange spoke at the conference in a similar manner on Saturday. Assange is living in asylum at the Ecuadorean embassy in London.