Luyken shot 5-of-13 from the floor and added six rebounds for the Cascades, who are making their second-straight nationals appearance. UFV finished tied for seventh place in 2013, and are the Canada West finalists at this year's Final 8.
"It's exciting. You know we've been to two regionals and gone 0-1 and 0-1 and last year was 0-2 at nationals which was disappointing for everybody," said UFV head coach Al Tuchscherer. "We wanted to come in this year with a little bit different approach to how we prepared and how we carried ourselves and I thought tonight was a good game and it was pretty business-like for us."
Fraser Valley will play No. 1 Windsor in the second semifinals on Saturday.
"We've got our work cut out for us tomorrow for sure, " said Tuchscherer.
Quebec MVP Mariam Sylla recorded a team-best 17 points and 11 rebounds for a double-double in a losing cause for the Martlets who are appearing in their ninth CIS championship tournament.
McGill will take on Laurier in the second consolation semifinal on Saturday.
Earlier, Miah-Marie Langlois scored a game-high 30 points and the top-ranked Windsor Lancers booked their spot in the semifinals of the with an 81-53 victory over the No. 8 Laurier Golden Hawks.
Angelina Carvery had a game-high 13 points as the second-seeded Saint Mary's Huskies earned a 71-51 quarter-final win over the No. 7 Alberta Pandas.
Rachelle Coward added 12 points and freshman Emily Jameson scored 10 for Saint Mary's, which improved to 30-0 this season.
Also, Kelsey Truslud poured in 22 points and grabbed 15 rebounds to propel the Saskatchewan Huskies to the semis with a 61-52 quarter-final victory over No. 6 Queen's Gaels.
Kabree Howard added 12 points, while Dalyce Emmerson had 11 boards for the Huskies, who are making their sixth appearance in the championships.
Liz Boag scored 18 points to lead Queen's, who is returning to the national spotlight after a 10-year absence.