Liverpool is two points clear of Chelsea in the Premier League after a 3-2 victory over third-place Manchester City, while Atletico leads La Liga by three points from Real Madrid following a 2-1 win at Getafe.
Here is a look at the action across Europe's main leagues:
Liverpool took command of the captivating Premier League title race by beating City in a match of wide-ranging emotions at Anfield, although Chelsea also has matters in its own hands after a 1-0 win at Swansea on Sunday.
Hull's 5-3 victory over third-tier Sheffield United in the second FA Cup semifinal, which set up a meeting with Arsenal in the final, was overshadowed by the latest installment in the fight for the league title that still has some way to run.
Seeking a first championship in 24 years, Liverpool is the favourite after taking its winning streak to 10 games thanks to Philippe Coutinho's match-clinching strike in the 78th minute against City.
Liverpool captain Steven Gerrard was in tears as he embraced his teammates and made a rousing speech at the end of an emotional contest that was played to a backdrop of tributes marking the 25th anniversary of the Hillsborough Stadium disaster, in which 96 Liverpool fans died.
City is now seven points behind Liverpool with two games in hand, while Chelsea stayed in control of its own fate after Demba Ba's goal secured three points in south Wales.
Liverpool is two points clear of Chelsea with four games left but the pair meet at Anfield in two weeks in what is likely to be a defining match in the race for the title.
Ba's winner in the 68th minute — a left-foot strike from the edge of the area — ended Swansea's stubborn resistance, with the hosts forced to play most of the match with 10 men following the 16th-minute dismissal of Chico Flores for two yellow cards.
Diego Costa was carried off with a bloody leg after scoring Atletico Madrid's second goal in a 2-0 win at 10-man Getafe on Sunday, although the team said its star striker escaped without a serious injury.
Atletico extended its Spanish league lead to three points with five rounds to play as it closes in on a surprising title.
Costa slammed into the post while poking in his 26th goal of the season in the 84th minute, hurting his left shin and requiring the stadium's medical crew to carry him off the pitch while he covered his face and muffled his screams.
While his teammates looked distraught as he writhed on the pitch, Atletico said less than 10 minutes after the match on Twitter that "luckily Diego Costa only has a cut after hitting the post."
Defender Diego Godin gave Atletico the lead in the 40th before Getafe's Alexis Ruano was dismissed with a red card in the 66th, with goalkeeper Jordi Codina saving Costa's penalty.
Atletico took advantage of Barcelona's loss on Saturday to open up a three-point lead over Real Madrid with Barcelona another point behind.
Mauro Icardi scored twice to help Inter Milan beat 10-man Sampdoria 4-0 in Serie A on Sunday and boost its hopes of qualifying for the Europa League.
Walter Samuel and Rodrigo Palacio also scored for Inter while Lopez had a penalty saved. Sampdoria played most of the match with 10 men after Eder was shown a second yellow card for his part in a brawl.
Inter remained fifth but will be boosted by Parma's 1-1 draw at Bologna and Lazio's 4-2 defeat at Napoli.
Hellas Verona's slim European hopes diminished as it lost 5-3 at home to Fiorentina.
Also, Chievo Verona beat Livorno 4-2 in a relegation battle, while Torino earned a 2-1 win against Genoa.
Bayer Leverkusen scored the fastest goal of the season on Sunday and beat Hertha Berlin 2-1 in the Bundesliga return for its new coach, moving up one place into fourth.
In the late match, Hoffenheim beat Augsburg 2-0 to come within two points of its opponent in eighth place.
Paris Saint-Germain failed to get over the disappointment of its Champions League exit as it lost 1-0 at Lyon in the French league on Sunday.
A wasteful PSG suffered a second straight loss for the first time this season but still tops the league with a 10-point lead over Monaco with just five rounds left. It lost 2-0 to Chelsea on Tuesday.
Lyon midfielder Jordan Ferri scored the winner with a low curling shot in the 31st minute.
Elsewhere, Saint-Etienne lost ground in the race for a Champions League spot by drawing 2-2 at Reims to trail third-place Lille by seven points.
In the Brittany derby, Serge Gakpe fired Nantes to a 1-0 win over Guingamp, helping his team inch closer to safety.