Kazmirek trailed two-time world champion Trey Hardee of the United States after three events but won the high jump and the 400 metres. The European under-23 champion tops the field with 4,478 points.
Hardee, who won the event three years ago, is second with 4,361 and Yordani Garcia of Cuba third with 4,260.
Theisen-Eaton gained 3,938 points from the first four events to lead Katarina Johnson-Thompson of Britain by 15 points and Nafissatou Thiam of Belgium by 18.
Dafne Schippers of the Netherlands, who won the 100 hurdles and the 200, is fourth with 3,865.