The deal will allow the bookseller to focus on developing its Nook digital software and away from building its own tablets.
The device will be a 7-inch Samsung Galaxy Tab 4 with Nook's digital reading software already on it. The tablet will be available at Barnes & Noble's 700 U.S. stores in early August. A price for the device will be announced then.
Barnes & Noble says it will continue to make and sell its $99 Nook GlowLight e-readers and provide customer support.
The company also says it is moving its Nook employees out of its Palo Alto, California, offices to save money. Employees will move to a smaller space in Santa Clara, California, by July 2015.