Ford, who began chemotherapy last month after doctors found a tumour in his abdomen, says doctors have told him there's a 50/50 survival rate for his condition.
But he says he always "sees the glass as half full" and is taking it "day to day."
Ford says it's hard to predict whether he'll be able to take part in any debates ahead of the Oct. 27 election because his energy levels vary so much.
Earlier in the day, the mayor said the hardest part of his health crisis has been explaining it to his children, adding he sometimes cries himself to sleep.
He said chemotherapy has "knocked the you-know-what" out of him but he remains optimistic.
"A lot of the stuff that I've gone through most of it's been self-inflicted but when you get hit with cancer this is by far the worst event, it's taken its toll on me," he said.
"I saw it with my dad, but I didn't feel it, I wasn't in his shoes, but I saw what he went through. And I just told the doctors, I just don't want to suffer."
Ford's father — Doug Ford Sr. — died of colon cancer in 2006.
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