Police say the driver of the truck failed to stop after the collision in the area of Dundas and Dupont streets.
The Toronto Police Service says due to the time change, November is traditionally the deadliest month of the year for pedestrians. It's often rainy and gets dark earlier.
Last November, there were nine pedestrian deaths in the city.
On Monday, police launched a campaign to make people aware of the dangers. The campaign will see officers heading into schools zones, pedestrian crossings and areas where there are seniors crossing the roads.
"Last year, there were nine fatalities in November and we want to reduce that," said Const. Clint Stibbe in an interview with CBC News after the safety campaign was launched..
Toronto has seen 23 pedestrian fatalities so far this year. Nine of these people have been seniors.
Pedestrian deaths represent more than half of all traffic fatalities in Toronto.