The Standard & Poor's 500 index fell 11 points, or 0.6 per cent, to close at 2,051 Friday. The Dow Jones industrial average dropped 141 points, or 0.8 per cent, to 17,672. The Nasdaq bucked the trend, rising seven points, or 0.2 per cent, to 4,757.
Shares of tissue and diaper maker Kimberly-Clark dropped after the company's earnings fell short of expectations. UPS slid after it cut its earnings outlook.
The yield on the 10-year Treasury slid to 1.80 per cent from 1.87 per cent late Thursday.
U.S. stock indexes ended the previous day with big gains after Europe's central bank unveiled a program to revitalize that region's economy.