A society spokeswoman says the dogs taken from a property in Milk River were emaciated, dehydrated and with badly matted fur.
Deanna Thompson says some had broken bones, gaping wounds and parasites.
The animals are a mix of huskies, Irish wolfhounds, malamutes and Komondors.
The SPCA is investigating.
Animal groups are stepping in to care for the dogs.
"We have been very lucky collaborating with different SPCAs, humane societies and rescue groups across Alberta and they've been placed in their shelters ... to be taken care of, spayed and neutered (and) put weight on," Thompson said.
"Then they all go up for adoption to find new, loving homes for them."
Thompson said her group has been around for 10 years and has seen a lot of neglect and abuse, but "nothing to this scale."
"Quite a few of these animals (had) body condition scores of one out of five or less, so it's going to take a long time to put some weight back on them and take care of their medical issues."
The Alberta Animal Rescue Crew Society is caring for more than 60 of the 200 animals right now, but hopes to farm another 20 or so out to other organizations.
Check out photos of some of the dogs seized from the property:
(WARNING: some photos may be disturbing for certain readers.)