Transit riders can use the Yonge line to travel to Union station or use the University line to travel to St. Andrew station.
The 506 Carlton, 505 Dundas, 501 Queen and 504 King streetcar routes are alternatives to connect between stations.
Regular service will resume Monday at 6 a.m.
There are two additional weekends scheduled for closure: Feb. 14-15 and Feb. 28 to March 1, tentatively, the TTC says.