They were down by four with the ball on the Patriots' one-yard line at second and goal when Wilson unloaded a pass intended for Ricardo Lockette.
The pass was caught by the Patriots' Malcolm Butler who returned the ball for a three-yard gain, giving the Patriots the ball, and the championship.
Patriots quarterback Tom Brady was elated by the play.
While the Seahawks' Richard Sherman was dejected by the game-ending interception.
Wilson discussed the decision to pass the ball during a post-game interview.
"You have different options, you can hand the ball off to Marshawn (Lynch), that's a great option, you can also throw it, which is a great option. We thought we had them and I thought it was going to be a touchdown when I threw it...I thought it was going to be game over," said Wilson.
Seahawks coach Pete Carroll also discussed the decision to pass instead of handing the ball to Marshawn Lynch.
"We really just didn't want to run against their goal line group there," said Carroll. "That's my fault totally,because everybody is like why don't you just run it, that's a real good thought, but we had plenty of time to win the game, in our minds we thought we would've done it on third and fourth down...we were playing for third and fourth down, give them no time left and it would have been just right."
Carroll was disappointed that the game came down to that play.
"For it to come down to a play like that, I hate that we have to live with that because we did everything right to win the football game," said Carroll.