Larry Beaucage (BOH'-cage) is receiving care in the city's St. Paul's Hospital and had removed the ring because his hands might swell from the medication he's receiving.
His wife, Gail, put the precious band in her purse and two days ago it was sitting on a window ledge while she helped her husband for a few minutes in the washroom.
When they returned, the purse was gone and the family has now filed a police report and is appealing to the person who took the bag to return the ring to the hospital, no questions asked.
The ring is made of white gold and has nine diamonds in a centre cluster.
Darcey Beaucage, the couple's son, tells Saskatoon radio station CKOM that he hopes the ring can be found before his father's death.
"He won't be going home from the hospital. The cancer has advanced quite rapidly over the last week and a half especially."
Beaucage said his father thought the ring was lost a few years ago, and he tore the couple's home apart looking for it before it turned up. He said the family has not told him it's missing again.
"It was incredibly important to my dad and it's one of the few things that we are going to have left of him afterwards. It would mean the world to my entire family. My mom is especially upset, but the rest of us are as well."
The couple's 60th anniversary is in May. (CKOM)