The report says less than one in five people use tobacco and while physical activity rates are rising, more than 60 per cent of people say they spend more than two hours a day in sedentary behaviour such as watching the television or surfing the Internet.
More than half of the region's population is considered overweight or obese, and more than one in five people report heavy alcohol use or binge drinking.
The figures are from 2011-12.
Dr. Julie Kryzanowski, deputy medical health officer for the region, says there appears to be inequity in health between those living in the most and least disadvantaged areas in Saskatoon.
Only 47 per cent in the poorer areas said their health was good or excellent, compared to 72 per cent in the higher end areas.