The Health Authorities Act takes effect Wednesday.
The new law also includes changes to the way health workers are represented in labour negotiations.
Four councils will now negotiate collective agreements on behalf of nursing, health care, support and administrative workers.
The Liberal government says the changes to the way health care is administered will help divert more resources to frontline health care.
The Opposition Progressive Conservatives and NDP say it remains to be seen whether the proposed changes will help improve the delivery of health care services.