The shooting took place at the Moka Espresso bar on Islington Avenue near Highway 7. Regular café patron Christopher de Simone, 24, was shot dead. Maria Voci, who worked at the café, was also killed.
Police do not have a clear description of the suspect. Const. Andy Pattenden with the York Regional Police said the description they currently have of the suspect is a dark-skinned man who was at the café at the time of the shooting. He fled the scene in a dark-coloured compact car.
Pattenden said police are combing through security footage from cameras that were mounted on the building. He said he can't speculate on the reason for the shooting.
"At this point in time we have no information to believe that this was a random person that approached the café and started shooting," Pattenden said in an interview with CBC Metro Morning host Matt Galloway this morning.
Pattenden urged residents to contact police with any information related to the shooting.
The area has been subject to violence in recent years: there have been four shootings in the past couple of years, two of which were related to organized crime.
Pattenden said the region is one of the safest in the country, despite Wednesday's violence.
"A significant amount of resources were deployed immediately into area to make sure the area was safe," he added.