His charge comes almost eight years after his 29-year-old wife was found dead in the couple's Saint-Laurent apartment on Christmas Day in 2007.
Police say Cheema was seen on Dec. 24, 2007 leaving the apartment on Deguire Street. He left their two children at a friend's place before disappearing.
An Interpol notice was issued, naming Cheema as one of Quebec's 10 most-wanted alleged criminals.
Investigators tracked him to California, and he was arrested in San Francisco on July 8.
Cheema, 36, was flown to Quebec and arrived Wednesday night.