Canada will be without injured captain Tyler Ardron when it wraps up Rugby World Cup play Tuesday against Romania in a meeting of winless teams at the tournament.
Veteran lock Jamie Cudmore will serve as skipper at England's Leicester City Stadium.
Ardron, who was out with a knee injury for close to two months prior to the World Cup, was forced to leave 19 minutes into the 41-18 loss to France last Thursday. Fullback Matt Evans is also unavailable through injury, joining Connor Braid (broken jaw, concussion) and Liam Underwood (knee) on the sidelines.
It's the consequence of four games in just 18 days.
In contrast France, after playing its first two games in five days, got seven days to prepare for Canada and has nine to get ready for Ireland.
Canada, ranked 18th in the world, had hoped to finish third in Pool D. While only the top two advance to the quarter-finals, the third-place team secures automatic qualification to the next World Cup.
With No. 4 Ireland and No. 7 France contesting the top two spots, No. 14 Italy seems destined to finish third with Canada and No. 17 Romania, both Tier 2 teams, looking to avoid the basement.
Canada is 3-2-0 all-time against Romania, although the Oaks have won the last two meetings 18-9 and 21-20.
Canada's record against the other teams in the pool is a combined 3-20-1.
"They bring a very physical game," Canadian coach Kieran Crowley, in a statement, said of the Romanians. "Like all of the teams we have played against at the Rugby World Cup they have got a strong scrum and are effective in the drive, so we know they are going to bring that physical approach to the clash and we have to match that and also put our own game on them."
The Canadians enter the game 0-3-0 in the tournament while Romania is 0-2-0. But Canada has one point to Romania's none courtesy of a bonus point gained in the 23-18 loss to Italy.
Canada, beaten 50-7 by Ireland in its tournament opener, has impressed at times with winger DTV van der Merwe turning heads. But it squandered a chance to upset Italy.
Romania lost 38-11 to France and 44-10 to Ireland. It wraps up pool play Oct. 11 against Italy.
Crowley has made seven changes, one positional, to the team that lost to France.
Ray Barkwill starts at hooker, with Aaron Carpenter moving to No. 8 to replace in a new-look back row alongside Jebb Sinclair and sevens captain John Moonlight.
Gord McRorie takes over for Phil Mack at scrum half while Jeff Hassler returns from injury in place of Phil Mackenzie on the wing. Harry Jones steps in for the injured Evans at fullback.
James Pritchard, called into the squad to replace Underwood, starts on the bench and so has a chance to set foot on the field for his fourth World Cup. Prop Jake Ilnicki, called up to replace the injured Jason Marshall on the eve of the tournament, is also among the reserves.
Romania's Welsh coach Lynn Howells has made seven changes for the game.
"We set two goals," Howells is quoted on rugbyworldcup.com. "The first one, we’ve achieved, as we showed that we can play against the Tier 1 nations.
"The second goal is that we would have two wins, and the reason is that we would go straight to Japan 2019. It gives us four years' preparation which would be huge for Romanian rugby. The Canadian game is a semifinal for us. It’s that important. The players have put in a lot of hard work and this is what they deserve."
Hubert Buydens, Prairie Wolf Pack, Saskatoon; Ray Barkwill, Ontario Blues, Niagara Falls, Ont.; Doug Wooldridge, Lindsay RFC, Lindsay, Ont.; Brett Beukeboom, Cornish Pirates (England), Lindsay, Ont.; Jamie Cudmore (capt.), Clermont Auvergne (France), Squamish, B.C.; Jebb Sinclair, London Irish, Fredericton; John Moonlight, James Bay AA, Pickering, Ont.; Aaron Carpenter, Cornish Pirates (England), Brantford, Ont.; Gordon McRorie, Calgary Hornets, Calgary; Nathan Hirayama, UVIC Vikes, Vancouver; DTH van der Merwe, Scarlets (Wales), Victoria; Nick Blevins, Calgary Hornets, Calgary,; Ciaran Hearn, Atlantic Rock, Conception Bay South, N.L.; Jeff Hassler, Ospreys (Wales), Okotoks, Alta.; Harry Jones, Capilano RFC, North Vancouver.
Benoit Piffero, Atlantic Rock, Montreal; Djustice Sears-Duru, Oakville Crusaders, Oakville, Ont,; Jake Ilnicki, Castaway Wanderers, Williams Lake, B.C.; Kyle Gilmour, Rotherham Titans (England), St. Albert, Alta.; Nanyak Dala, Castaway Wanderers, Saskatoon; Phil Mack, James Bay AA, Victoria; Conor Trainor, UBCOB Ravens, Vancouver; James Pritchard, Bedford Blues (England), Parkes, Australia.
Follow @NeilMDavidson on Twitter
Neil Davidson, The Canadian Press