WASHINGTON — Sen. John McCain's
McCain underwent surgery last week to have a blood clot removed from above his left eye, and that clot turned out to be a sign that a
Here are some things to know about glioblastomas:
McCain's doctors at the Mayo Clinic said they managed to remove all of the
But this kind of
SURGERY DOESN"T CURE
McCain's Mayo doctors said the senator's next treatment options may include a combination of chemotherapy and radiation.
That's standard, and can take weeks to months. Even among those who respond to initial treatment, the cancer can come back, and often within 12 to 24 months. The American Cancer Society puts the five-year survival rate for patients over 55 at about 4
That said, "patients with certain types of mutations or genetic profiles can live longer," five years or more, cautioned Dr. Michael Lim, a Johns Hopkins University neurosurgeon.
He estimates that subset accounts for about 10
Mount Sinai's Bederson tells his own glioblastoma patients that he knows they'll look up the grim statistics, but he wants them to remember that some people do beat the odds for long periods.
"It's a small number. But that's the hope my patients have when they leave my office," he said.
Brain tumors, including glioblastomas, frequently are diagnosed only after the patient suffers symptoms such as headaches or seizures. Depending on where in the brain the
McCain's office hasn't said if he reported any symptoms, instead saying he had the blood clot removed after a routine physical exam.
Tumors in the frontal lobe tend not to cause symptoms until they're fairly large, Lim said.
BLOOD CLOTS AND CANCER
Sometimes blood clots, too, are an early sign of a brain
Where the leak and subsequent clot occurred in the brain would determine if there were any temporary symptoms from that bleed itself, Lim explained.
HOW OFTEN IT STRIKES
Glioblastomas (GLEE'-oh-blas-TOH'-muhs) are most common in adults. According to the American Brain Tumor Association, an estimated 12,390 cases are expected to be diagnosed this year.
McCain is a long-term survivor of melanoma, a deadly skin cancer. But doctors classified this new cancer as a "primary
Scientists are testing a variety of new approaches to treat glioblastomas, and both newly diagnosed patients and those with recurrent disease often are advised to consider options offered in clinical trials .
Several attempts aim at spurring the patient's immune system to attack the
Also being attempted is CAR-T cell therapy, where doctors genetically engineer a patient's immune cells to better attack their
Recently a cap-like device that makes electric fields to fight cancer has been shown to improve survival odds for people with glioblastomas.