The actor and comedian posted a photo Tuesday of the two smiling at each other during a family Christmas visit, writing: "We had so much fun that day. She was so sharp and quick on her feet. She could make me laugh so hard."
The fashion designer, who was married to the "Saturday Night Live" alum's brother Andy, died in an apparent suicide at age 55 earlier in the day.
On Twitter, Spade shared a photo of his sister-in-law at his book-signing. He praised her beauty and sense of humor, and repeated the advice from his Instagram photo. "It's a rough world out there people," he wrote. "Try to hang on."
Are you in a crisis? If you need help, contact Crisis Services Canada at their website or by calling 1-833-456-4566. If you know someone who may be having thoughts of suicide, visit CAMH's resource to learn how to talk about suicide with the person you're worried about.