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06/13/2013 07:33 EDT | Updated 08/13/2013 01:12 EDT

John Stamos: Lori Loughlin 'Could Be The One That Got Away' (VIDEO)

Could Uncle Jesse and Aunt Becky have been real life husband and wife?

Actor John Stamos joined Abby Huntsman Thursday and said that his former "Full House" co-star Lori Loughlin may be "the one that got away."